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Non-HDL cholesterol levels

C10orf88 · rs9423289

What the study found

Who was studied 1,320,016 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0199 lower (95% confidence interval 0.017-0.023); p = 9 × 10−25.

How common The C allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 10, band 10q26.13 — in an intron of C10orf88.

What each result means

C/C Two copies of the version the research linked to Non-HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Non-HDL cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Non-HDL cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs9423289

What is rs9423289?

rs9423289 is a single position in the genome, in or near the C10orf88 gene. Published research associates it with non-hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9423289 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9423289 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Non-HDL cholesterol levels (rs9423289). MyGeneLog™. https://www.mygenelog.com/variants/rs9423289

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