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High density lipoprotein cholesterol levels

SF3B3 · rs940922629

What the study found

Who was studied 1,320,016 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.399 lower (95% confidence interval 0.31-0.49); p = 6 × 10−11.

How common The C allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 16, band 16q22.1 — in an intron of SF3B3.

What each result means

C/C Two copies of the version the research linked to High density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to High density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to High density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs940922629

What is rs940922629?

rs940922629 is a single position in the genome, in or near the SF3B3 gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs940922629 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs940922629 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High density lipoprotein cholesterol levels (rs940922629). MyGeneLog™. https://www.mygenelog.com/variants/rs940922629

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