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Thrombin-activatable fibrinolysis inhibitor activation peptide

CPB2 · rs940

What the study found

Who was studied 3,124 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.16 higher (95% confidence interval 0.13-0.19); p = 1 × 10−27.

How common The G allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 13, band 13q14.13 — in the 3′ untranslated region of CPB2-AS1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Thrombin-activatable fibrinolysis inhibitor activation peptide — no copies of the reported risk allele.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Thrombin-activatable fibrinolysis inhibitor activation peptide.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Thrombin-activatable fibrinolysis inhibitor activation peptide compared to the general population.
Source

Questions about rs940

What is rs940?

rs940 is a single position in the genome, in or near the CPB2 gene. Published research associates it with thrombin-activatable fibrinolysis inhibitor activation peptide. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs940 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs940 come from?

GWAS Catalog, Thromb Haemost 2018, PMID:29378355. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Thrombin-activatable fibrinolysis inhibitor activation peptide (rs940). MyGeneLog™. https://www.mygenelog.com/variants/rs940

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