Standard

Refractive error

RASGRF1 · rs939658

Where this position leads

Condition: Myopia

rs939658 Condition: Myopia Myopia Condition rs939658 rs939658 RASGRF1

What the study found

Who was studied 4,270 European ancestry individuals; replicated in 13,414 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.15 diopter lower (95% confidence interval 0.10-0.20); p = 2 × 10−9.

How common The G allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 15, band 15q25.1 — in an intron of ANKRD34C-AS1.

What each result means

A/A No copy of the version the research linked to Refractive error. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Refractive error. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Refractive error. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs939658

What is rs939658?

rs939658 is a single position in the genome, in or near the RASGRF1 gene. Published research associates it with refractive error. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs939658 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs939658?

Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs939658 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs939658 come from?

GWAS Catalog, Nat Genet 2010, PMID:20835236. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Refractive error (rs939658). MyGeneLog™. https://www.mygenelog.com/variants/rs939658

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