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Who was studied 282 Japanese ancestry cases, 426 Japanese ancestry controls; replicated in 320 Japanese ancestry cases, 1,622 Japanese ancestry controls.
The effect
Each copy of the G allele carried 1.86 times the odds of Psoriasis vulgaris (95% confidence interval 1.59-2.18); p = 7 × 10−15.
How common The G allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of MUC22.
What each result means
A/ANo copy of the version the research linked to Psoriasis vulgaris. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Psoriasis vulgaris. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Psoriasis vulgaris. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of investigative dermatology · 2018 · PMID 29031612
Questions about rs9394026
What is rs9394026?
rs9394026 is a single position in the genome, in or near the HLA gene. Published research associates it with psoriasis vulgaris. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9394026 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
Does having rs9394026 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9394026 come from?
GWAS Catalog, J Invest Dermatol 2017, PMID:29031612. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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