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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 22,882 European ancestry individuals, 4,005 African ancestry individuals, 1,392 Thai ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.00134 lower (95% confidence interval 0.0012-0.0015); p = 5 × 10−113.
How common The C allele had a frequency of about 24% in the people studied.
What each result means
C/CTwo copies of the version the research linked to Fetal hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Fetal hemoglobin levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Fetal hemoglobin levels. This is the starting point the study compared everyone against.
rs9389271 is a single position in the genome, in or near the near HBS1L gene. Published research associates it with fetal hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs9389271 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9389271 come from?
GWAS Catalog, Nature 2026, PMID:42816612. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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