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Urinary sodium excretion

FGF21 · rs9387963

What the study found

Who was studied 446,237 European ancestry individuals; replicated in 7,612 African ancestry individuals, 10,095 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0082 lower (95% confidence interval 0.0058-0.0106); p = 5 × 10−11.

How common The G allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 6, band 6q16.1 — between genes, 49.2 kb from MIR2113.

What each result means

A/A No copy of the version the research linked to Urinary sodium excretion. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Urinary sodium excretion. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Urinary sodium excretion. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9387963

What is rs9387963?

rs9387963 is a single position in the genome, in or near the FGF21 gene. Published research associates it with urinary sodium excretion. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9387963 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9387963 come from?

GWAS Catalog, Nature communications 2019, PMID:31409800. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary sodium excretion (rs9387963). MyGeneLog™. https://www.mygenelog.com/variants/rs9387963

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