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Smoking initiation

MIR2113 · rs9375328

What the study found

Who was studied 842,717 European ancestry individuals.

The effect Each copy of the C allele carried 1.03 times the odds of Smoking initiation; p = 1 × 10−11.

Where it sits Chromosome 6, band 6q16.1 — between genes, 83.5 kb from EIF4EBP2P3.

What each result means

C/C Two copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
T/T No copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
Source

Questions about rs9375328

What is rs9375328?

rs9375328 is a single position in the genome, in or near the MIR2113 gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9375328 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9375328 come from?

GWAS Catalog, Nature communications 2020, PMID:33082346. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Smoking initiation (rs9375328). MyGeneLog™. https://www.mygenelog.com/variants/rs9375328

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