Standard

Bone mineral density (spine)

ESR1 · rs9371538

Where this position leads

Condition: Spine Bone Mineral Density

rs9371538 Condition: Spine Bone Mineral Density Spine Bone Mineral Density Condition rs9371538 rs9371538 ESR1

What the study found

Who was studied 2,729 Korean ancestry individuals; replicated in 1,547 Han Chinese ancestry individuals, 3,237 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.14 lower; p = 3 × 10−6.

How common The T allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 6, band 6q25.1 — in an intron of CCDC170.

What each result means

A/A No copy of the version the research linked to Bone mineral density (spine). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Bone mineral density (spine). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Bone mineral density (spine). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9371538

What is rs9371538?

rs9371538 is a single position in the genome, in or near the ESR1 gene. Published research associates it with bone mineral density (spine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9371538 linked to?

On MyGeneLog this position is linked to Spine Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.

Does having rs9371538 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9371538 come from?

GWAS Catalog, Bone 2016, PMID:27424934. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Bone mineral density (spine) (rs9371538). MyGeneLog™. https://www.mygenelog.com/variants/rs9371538

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