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Standard

Height

CD2AP · rs9369714

Strength of the evidence

2 / 4

Its strongest genetic-study result is p = 10−33, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 455,180 Hispanic or Latin American individuals.

The effect Each copy of the G allele shifted the measure 0.0269 lower (95% confidence interval 0.023-0.031); p = 9 × 10−34.

How common The G allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 6, band 6p12.3 — in an intron of CD2AP.

How common each version is

AG
Korean KRGDB
A 28.4% · G 71.6%
Korean Korea4K
A 28.6% · G 71.4%
Korean Korea1K
A 27.8% · G 72.2%
Japanese ToMMo
A 30.4% · G 69.5%
Vietnamese
A 37.7% · G 62.3%
World gnomAD
A 60.4% · G 39.6%
World 1000 Genomes
A 52.3% · G 47.7%
World TOPMed
A 59.3% · G 40.7%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

A/A No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Quoting this page

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Height (rs9369714). MyGeneLog™. https://www.mygenelog.com/variants/rs9369714

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