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Severe coronary stenosis

near SFTA2 · rs9368648

What the study found

Who was studied 1,734 Middle Eastern ancestry cases, 757 Middle Eastern ancestry controls.

The effect The reported allele is T; the catalogue records no effect size ; p = 3 × 10−9.

Where it sits Chromosome 6, band 6p21.33 — between genes, 0.5 kb from SFTA2.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Severe coronary stenosis — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Severe coronary stenosis.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Severe coronary stenosis compared to the general population.
Source

Questions about rs9368648

What is rs9368648?

rs9368648 is a single position in the genome, in or near the near SFTA2 gene. Published research associates it with severe coronary stenosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9368648 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9368648 come from?

GWAS Catalog, BMC Med Genomics 2021, PMID:33766035. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Severe coronary stenosis (rs9368648). MyGeneLog™. https://www.mygenelog.com/variants/rs9368648

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