Sensitive

Type 2 diabetes (age of onset)

CDKAL1 · rs9368219

Where this position leads

Condition: Type 2 Diabetes

rs9368219 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs9368219 rs9368219 CDKAL1

What the study found

Who was studied 9,103 South Indian ancestry individuals, 24,898 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.05 lower (95% confidence interval -0.4008-0.5008); p = 2 × 10−8.

How common The T allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — in an intron of CDKAL1.

What each result means

C/C No copy of the version the research linked to Type 2 diabetes (age of onset). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Type 2 diabetes (age of onset). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Type 2 diabetes (age of onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9368219

What is rs9368219?

rs9368219 is a single position in the genome, in or near the CDKAL1 gene. Published research associates it with type 2 diabetes (age of onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9368219 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs9368219 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9368219 come from?

GWAS Catalog, Diabetes care 2023, PMID:37308106. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (age of onset) (rs9368219). MyGeneLog™. https://www.mygenelog.com/variants/rs9368219

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