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Chronic hepatitis B infection

HLA-DPA3 · rs9366816

Where this position leads

Condition: Chronic Hepatitis B

rs9366816 Condition: Chronic Hepatitis B Chronic Hepatitis B Condition Topic: Infection and immunity Infection and immunity Topic rs9366816 rs9366816 HLA-DPA3

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 321 Chinese ancestry cases, 304 Chinese ancestry controls; replicated in 1,302 Chinese ancestry cases, 761 Chinese ancestry controls.

The effect Each copy of the T allele carried 1.49 times the odds of Chronic hepatitis B infection (95% confidence interval 1.33-1.66); p = 1 × 10−12.

How common The T allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of LOC105375021.

What each result means

C/C Two copies of the version the research linked to Chronic hepatitis B infection. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Chronic hepatitis B infection. That is a smaller link than two copies.
T/T No copy of the version the research linked to Chronic hepatitis B infection. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9366816

What is rs9366816?

rs9366816 is a single position in the genome, in or near the HLA-DPA3 gene. Published research associates it with chronic hepatitis b infection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9366816 linked to?

On MyGeneLog this position is linked to Chronic Hepatitis B. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9366816?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (3 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9366816 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9366816 come from?

GWAS Catalog, PLoS One 2014, PMID:24940741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Chronic hepatitis B infection (rs9366816). MyGeneLog™. https://www.mygenelog.com/variants/rs9366816

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