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Thyroid stimulating hormone levels

ULK3 · rs936228

What the study found

Who was studied 482,873 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.014 higher (95% confidence interval 0.01-0.018); p = 1 × 10−9.

How common The C allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 15, band 15q24.1 — in an intron of ULK3.

What each result means

C/C Two copies of the version the research linked to Thyroid stimulating hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Thyroid stimulating hormone levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Thyroid stimulating hormone levels. This is the starting point the study compared everyone against.
Source

Questions about rs936228

What is rs936228?

rs936228 is a single position in the genome, in or near the ULK3 gene. Published research associates it with thyroid stimulating hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs936228 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs936228 come from?

GWAS Catalog, Nature genetics 2025, PMID:41238958. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid stimulating hormone levels (rs936228). MyGeneLog™. https://www.mygenelog.com/variants/rs936228

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