Sensitive

Alzheimer's disease or family history of Alzheimer's disease

near PNRC2P1 · rs935208076

Where this position leads

Condition: Alzheimer's Disease

rs935208076 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs935208076 rs935208076 near PNRC2P1

What the study found

Who was studied 2,559 Hispanic cases, 5,908 Hispanic controls, 615 African ancestry cases, 2,560 African ancestry controls, 767 Admixed-American ancestry cases, 14,907 Admixed-American ancestry controls, 3,097 European ancestry cases, 2,077 European ancestry controls, 146 East or South Asian cases, 1,285 East or South Asian controls, 8 Middle-Eastern ancestry cases, 40 Middle-Eastern ancestry controls.

The effect Each copy of the C allele carried 8.10 times the odds of Alzheimer's disease or family history of Alzheimer's disease (95% confidence interval 3.9-17.0); p = 2 × 10−8.

Where it sits Chromosome 1, band 1p12 — between genes, 35.1 kb from PNRC2P1.

What each result means

C/C Two copies of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. This is the starting point the study compared everyone against.
Source

Questions about rs935208076

What is rs935208076?

rs935208076 is a single position in the genome, in or near the near PNRC2P1 gene. Published research associates it with alzheimer's disease or family history of alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs935208076 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs935208076 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs935208076 come from?

GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2026, PMID:41755704. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease or family history of Alzheimer's disease (rs935208076). MyGeneLog™. https://www.mygenelog.com/variants/rs935208076

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