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Who was studied 8,309 European ancestry cases, 7,366 European ancestry controls; replicated in 10,523 European ancestry cases, 28,231 European ancestry controls.
The effect
Each copy of the C allele carried 1.11 times the odds of Alzheimer's disease (late onset) (95% confidence interval 1.07-1.15); p = 9 × 10−9.
How common The C allele had a frequency of about 27% in the people studied.
Where it sits Chromosome 6, band 6p12.3 — in an intron of CD2AP.
What each result means
C/CTwo copies of the version the research linked to Alzheimer's disease (late onset). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Alzheimer's disease (late onset). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Alzheimer's disease (late onset). This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs9349407
What is rs9349407?
rs9349407 is a single position in the genome, in or near the CD2AP gene. Published research associates it with alzheimer's disease (late onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9349407 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs9349407?
Subjects that appear in the title or abstract of the same papers as this rsID include learning and focus (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs9349407 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9349407 come from?
GWAS Catalog, Nat Genet 2011, PMID:21460841. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 535258222225Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity5Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total53Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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