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Serum levels of protein IGF1

near Y_RNA · rs934073

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 14,602 European ancestry women.

The effect Each copy of the C allele shifted the measure 4.42 zscore lower; p = 1 × 10−5.

Where it sits Chromosome 2, band 2p23.3 — between genes, 17.1 kb from Y_RNA.

What each result means

C/C Two copies of the version the research linked to Serum levels of protein IGF1. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Serum levels of protein IGF1. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum levels of protein IGF1. This is the starting point the study compared everyone against.
Source
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S
and 74 more — show all
Chen MH, Chen TC, Chen YD, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JA, Jansson JO, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJ, Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh HW, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC
CHARGE Longevity Working Group · Body Composition Genetics Consortium
Aging cell · 2016 · PMID 27329260 · open access

Questions about rs934073

What is rs934073?

rs934073 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with serum levels of protein igf1. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs934073 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs934073 come from?

GWAS Catalog, Aging cell 2016, PMID:27329260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum levels of protein IGF1 (rs934073). MyGeneLog™. https://www.mygenelog.com/variants/rs934073

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