Standard

High density lipoprotein cholesterol levels

MGST1 · rs9332891

What the study found

Who was studied 99,432 Admixed African or African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.127 lower (95% confidence interval 0.099-0.154); p = 8 × 10−19.

How common The G allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 12, band 12p12.3 — in an intron of MGST1.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of High density lipoprotein cholesterol levels compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with High density lipoprotein cholesterol levels.
T/T Published research associates this genotype with typical/baseline likelihood of High density lipoprotein cholesterol levels — no copies of the reported risk allele.
Source

Questions about rs9332891

What is rs9332891?

rs9332891 is a single position in the genome, in or near the MGST1 gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9332891 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9332891 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

High density lipoprotein cholesterol levels (rs9332891). MyGeneLog™. https://www.mygenelog.com/variants/rs9332891

← See all variants