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SELP protein levels

F5 · rs9332688

Where this position leads

Condition: Celiac Disease

Drug: Combined hormonal contraceptives

rs9332688 Condition: Celiac Disease Celiac Disease Condition Drug: Combined hormonal contraceptives Combined hormonal contraceptives Drug rs9332688 rs9332688 F5

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.184 higher (95% confidence interval 0.13-0.24); p = 1 × 10−11.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of F5.

What each result means

A/A Two copies of the version the research linked to SELP protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to SELP protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to SELP protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs9332688

What is rs9332688?

rs9332688 is a single position in the genome, in or near the F5 gene. Published research associates it with selp protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9332688 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does rs9332688 affect how medicines work?

F5 carries pharmacogenomic findings for Combined hormonal contraceptives. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs9332688 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9332688 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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SELP protein levels (rs9332688). MyGeneLog™. https://www.mygenelog.com/variants/rs9332688

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