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Medication use (thyroid preparations)

near MIR3939 · rs933243

What the study found

Who was studied 24,832 European ancestry cases, 280,750 European ancestry controls, 3,103 East Asian ancestry cases, 175,623 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.113 lower (95% confidence interval 0.096-0.131); p = 3 × 10−36.

Where it sits Chromosome 6, band 6q27 — between genes, 7.4 kb from MIR3939.

What each result means

A/A Two copies of the version the research linked to Medication use (thyroid preparations). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Medication use (thyroid preparations). That is a smaller link than two copies.
C/C No copy of the version the research linked to Medication use (thyroid preparations). This is the starting point the study compared everyone against.
Source

Questions about rs933243

What is rs933243?

rs933243 is a single position in the genome, in or near the near MIR3939 gene. Published research associates it with medication use (thyroid preparations). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs933243 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs933243 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Medication use (thyroid preparations) (rs933243). MyGeneLog™. https://www.mygenelog.com/variants/rs933243

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