Standard

Myopia (pathological)

MIPEP · rs9318086

Where this position leads

Condition: Myopia

rs9318086 Condition: Myopia Myopia Condition Topic: Short-sightedness and screens Short-sightedness and screens Topic rs9318086 rs9318086 MIPEP

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 419 Han Chinese ancestry high myopia cases, 669 Han Chinese ancestry controls; replicated in 2,803 East Asian ancestry high myopia cases, 5,642 East Asian ancestry controls.

The effect Each copy of the A allele carried 1.32 times the odds of Myopia (pathological) (95% confidence interval 1.19-1.46); p = 2 × 10−16.

How common The A allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 13, band 13q12.12 — in an intron of MIPEP.

What each result means

A/A Two copies of the version the research linked to Myopia (pathological). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Myopia (pathological). That is a smaller link than two copies.
G/G No copy of the version the research linked to Myopia (pathological). This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9318086

What is rs9318086?

rs9318086 is a single position in the genome, in or near the MIPEP gene. Published research associates it with myopia (pathological). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9318086 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9318086?

Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (4 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9318086 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9318086 come from?

GWAS Catalog, Am J Hum Genet 2011, PMID:21640322. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Myopia (pathological) (rs9318086). MyGeneLog™. https://www.mygenelog.com/variants/rs9318086

← See all variants