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Male-pattern baldness

near HMGB1 · rs9315009

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs9315009 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs9315009 rs9315009 near HMGB1

What the study found

Who was studied 205,327 European ancestry males.

The effect Each copy of the C allele shifted the measure 0.0226 lower (95% confidence interval 0.016-0.029); p = 3 × 10−11.

How common The C allele had a frequency of about 30% in the people studied.

Where it sits Chromosome 13, band 13q12.3 — between genes, 5.4 kb from HMGB1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
T/T Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
Source

Questions about rs9315009

What is rs9315009?

rs9315009 is a single position in the genome, in or near the near HMGB1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9315009 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs9315009 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9315009 come from?

GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs9315009). MyGeneLog™. https://www.mygenelog.com/variants/rs9315009

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