Standard
Classic bladder exstrophy
ISL1 · rs9291768
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Classic bladder exstrophy — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Classic bladder exstrophy.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Classic bladder exstrophy compared to the general population.
Source
Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy
Draaken M,
Knapp M,
Pennimpede T,
Schmidt JM,
Ebert AK,
Rösch W,
Stein R,
Utsch B,
Hirsch K,
Boemers TM,
Mangold E,
Heilmann S
and 9 more — show all
PLoS genetics · 2015 · PMID 25763902 · open access
Questions about rs9291768
What is rs9291768?
rs9291768 is a single position in the genome, in or near the ISL1 gene. Published research associates it with classic bladder exstrophy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs9291768 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9291768 come from?
GWAS Catalog, PLoS Genet 2015, PMID:25763902. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants