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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 77 Japanese ancestry cases, 924 Japanese ancestry controls; replicated in 91 Japanese ancestry cases, 435 Japanese ancestry controls.
The effect
Each copy of the A allele carried 3.53 times the odds of Wheat-dependent exercise-induced anaphylaxis (95% confidence interval 2.45-5.09); p = 1 × 10−11.
How common The A allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — in an intron of HLA-DPB2.
What each result means
A/ATwo copies of the version the research linked to Wheat-dependent exercise-induced anaphylaxis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Wheat-dependent exercise-induced anaphylaxis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Wheat-dependent exercise-induced anaphylaxis. This is the starting point the study compared everyone against.
American journal of human genetics · 2021 · PMID 34246321
Questions about rs9277630
What is rs9277630?
rs9277630 is a single position in the genome, in or near the HLA-DPB2 gene. Published research associates it with wheat-dependent exercise-induced anaphylaxis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs9277630 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9277630 come from?
GWAS Catalog, American journal of human genetics 2021, PMID:34246321. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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