Extraintestinal manifestations in inflammatory bowel disease (primary sclerosing cholangitis)
near HLA-DQA2 · rs9276456
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 286 European ancestry cases, 11,738 European ancestry controls.
The effect
Each copy of the G allele carried 2.76 times the odds of Extraintestinal manifestations in inflammatory bowel disease (primary sclerosing cholangitis) (95% confidence interval 2.012-3.773); p = 3 × 10−10.
Where it sits Chromosome 6, band 6p21.32 — between genes, 1 kb from HLA-DQA2.
What each result means
A/ANo copy of the version the research linked to Extraintestinal manifestations in inflammatory bowel disease (primary sclerosing cholangitis). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Extraintestinal manifestations in inflammatory bowel disease (primary sclerosing cholangitis). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Extraintestinal manifestations in inflammatory bowel disease (primary sclerosing cholangitis). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs9276456 is a single position in the genome, in or near the near HLA-DQA2 gene. Published research associates it with extraintestinal manifestations in inflammatory bowel disease (primary sclerosing cholangitis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9276456 linked to?
On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs9276456 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9276456 come from?
GWAS Catalog, Gastroenterology 2024, PMID:38490347. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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