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Immunoglobulin A vasculitis

near MTCO3P1 · rs9275582

What the study found

Who was studied 46 Finnish ancestry cases, 18,757 Finnish ancestry controls.

The effect Each copy of the T allele carried 4.54 times the odds of Immunoglobulin A vasculitis (95% confidence interval 3.45-5.98); p = 1 × 10−9.

How common The T allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 5.3 kb from MTCO3P1.

What each result means

C/C No copy of the version the research linked to Immunoglobulin A vasculitis. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Immunoglobulin A vasculitis. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Immunoglobulin A vasculitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9275582

What is rs9275582?

rs9275582 is a single position in the genome, in or near the near MTCO3P1 gene. Published research associates it with immunoglobulin a vasculitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9275582 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9275582 come from?

GWAS Catalog, Pediatric nephrology (Berlin, Germany) 2021, PMID:33591409. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Immunoglobulin A vasculitis (rs9275582). MyGeneLog™. https://www.mygenelog.com/variants/rs9275582

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