Standard

diastolic blood pressure (DBP, minimum, inv-normal transformed)

near HLA-DQB1 · rs9275036

Where this position leads

Condition: Blood Pressure

rs9275036 Condition: Blood Pressure Blood Pressure Condition rs9275036 rs9275036 near HLA-DQB1

What the study found

Who was studied 119,331 African American or Afro-Caribbean individuals, 57,991 Hispanic or Latin American individuals, 6,420 East Asian ancestry individuals, 425,735 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0201 higher (95% confidence interval 0.015-0.026); p = 2 × 10−12.

How common The T allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 9.2 kb from HLA-DQB1.

What each result means

C/C No copy of the version the research linked to diastolic blood pressure (DBP, minimum, inv-normal transformed). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to diastolic blood pressure (DBP, minimum, inv-normal transformed). That is a smaller link than two copies.
T/T Two copies of the version the research linked to diastolic blood pressure (DBP, minimum, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9275036

What is rs9275036?

rs9275036 is a single position in the genome, in or near the near HLA-DQB1 gene. Published research associates it with diastolic blood pressure (dbp, minimum, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9275036 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs9275036 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9275036 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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diastolic blood pressure (DBP, minimum, inv-normal transformed) (rs9275036). MyGeneLog™. https://www.mygenelog.com/variants/rs9275036

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