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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 64,962 European ancestry cases, 410,350 European ancestry controls.
The effect
Each copy of the T allele carried 0.90 times the odds of Cancer (pleiotropy) (95% confidence interval 0.878-0.924); p = 9 × 10−16.
Where it sits Chromosome 6, band 6p21.32 — in a non-coding transcript of HLA-DQB1.
What each result means
A/ANo copy of the version the research linked to Cancer (pleiotropy). This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Cancer (pleiotropy). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2020 · PMID 32887889 · open access
Questions about rs9273501
What is rs9273501?
rs9273501 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs9273501 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9273501 come from?
GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cancer (pleiotropy) (rs9273501). MyGeneLog™. https://www.mygenelog.com/variants/rs9273501