0 1412227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,068 European ancestry cases, 40,360 European ancestry controls; replicated in 4,301 European ancestry cases, 48,609 European ancestry controls, 297 African American cases, 1,335 African American controls.
The effect
Each copy of the A allele carried 1.20 times the odds of Asthma-COPD overlap syndrome (95% confidence interval 1.161-1.239); p = 9 × 10−28.
How common The A allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — in the 3′ untranslated region of HLA-DQB1.
What each result means
A/ATwo copies of the version the research linked to Asthma-COPD overlap syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Asthma-COPD overlap syndrome. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Asthma-COPD overlap syndrome. This is the starting point the study compared everyone against.
rs9273410 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with asthma-copd overlap syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9273410 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs9273410 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9273410 come from?
GWAS Catalog, Chest 2022, PMID:35104449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1412227Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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