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Who was studied 9,209 European ancestry cases, 47,428 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 6 × 10−15.
How common The A allele had a frequency of about 44% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — in an intron of HLA-DQA1.
What each result means
A/ATwo copies of the version the research linked to Asthma (additive model). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Asthma (additive model). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Asthma (additive model). This is the starting point the study compared everyone against.
Nature communications · 2021 · PMID 33893285 · open access
Questions about rs9272521
What is rs9272521?
rs9272521 is a single position in the genome, in or near the HLA-DQA1 gene. Published research associates it with asthma (additive model). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9272521 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs9272521 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9272521 come from?
GWAS Catalog, Nature communications 2021, PMID:33893285. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 71213Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others3Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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