0 132110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,639 East Asian ancestry cases, 2,410 East Asian ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.574 lower (95% confidence interval 0.48-0.66); p = 4 × 10−36.
Where it sits Chromosome 6, band 6p21.32 — between genes, 2.1 kb from HLA-DRB1.
What each result means
C/CTwo copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
rs9270539 is a single position in the genome, in or near the near HLA-DRB1 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9270539 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs9270539 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9270539 come from?
GWAS Catalog, Molecular genetics and genomics : MGG 2021, PMID:34076728. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 132110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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