Sensitive

Basal cell carcinoma (PheCode 172.21)

HLA-DRB9 · rs9269080

Where this position leads

Condition: Basal Cell Carcinoma

rs9269080 Condition: Basal Cell Carcinoma Basal Cell Carcinoma Condition rs9269080 rs9269080 HLA-DRB9

What the study found

Who was studied 31,142 European ancestry cases, 404,406 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0819 higher (95% confidence interval 0.063-0.101); p = 1 × 10−19.

How common The G allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in a non-coding transcript of HLA-DRB9.

What each result means

A/A No copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9269080

What is rs9269080?

rs9269080 is a single position in the genome, in or near the HLA-DRB9 gene. Published research associates it with basal cell carcinoma (phecode 172.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9269080 linked to?

On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs9269080 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9269080 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Basal cell carcinoma (PheCode 172.21) (rs9269080). MyGeneLog™. https://www.mygenelog.com/variants/rs9269080

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