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Systolic blood pressure

FHL1 · rs926905

Where this position leads

Condition: Blood Pressure

rs926905 Condition: Blood Pressure Blood Pressure Condition rs926905 rs926905 FHL1

What the study found

Who was studied 349,328 British ancestry individuals; replicated in 144,022 European ancestry,African ancestry,Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.01 higher (95% confidence interval 0.0061-0.0139); p = 5 × 10−10.

Where it sits Chromosome X, band Xq26.3 — in an intron of FHL1.

What each result means

G/G Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs926905

What is rs926905?

rs926905 is a single position in the genome, in or near the FHL1 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs926905 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs926905 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs926905 come from?

GWAS Catalog, Nature medicine 2024, PMID:38459180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs926905). MyGeneLog™. https://www.mygenelog.com/variants/rs926905

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