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Asthma

HLA-DRA · rs9268516

Where this position leads

Condition: Asthma

rs9268516 Condition: Asthma Asthma Condition rs9268516 rs9268516 HLA-DRA

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Asthma — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Asthma.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Asthma compared to the general population.
Source
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA
Ramasamy A, Kuokkanen M, Vedantam S, Gajdos ZK, Couto Alves A, Lyon HN, Ferreira MA, Strachan DP, Zhao JH, Abramson MJ, Brown MA, Coin L
and 34 more — show all
Dharmage SC, Duffy DL, Haahtela T, Heath AC, Janson C, Kähönen M, Khaw KT, Laitinen J, Le Souef P, Lehtimäki T, Madden PA, Marks GB, Martin NG, Matheson MC, Palmer CD, Palotie A, Pouta A, Robertson CF, Viikari J, Widen E, Wjst M, Jarvis DL, Montgomery GW, Thompson PJ, Wareham N, Eriksson J, Jousilahti P, Laitinen T, Pekkanen J, Raitakari OT, O'Connor GT, Salomaa V, Jarvelin MR, Hirschhorn JN
Australian Asthma Genetics Consortium Collaborators
PloS one · 2012 · PMID 23028483 · open access

Questions about rs9268516

What is rs9268516?

rs9268516 is a single position in the genome, in or near the HLA-DRA gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9268516 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs9268516 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9268516 come from?

GWAS Catalog, PLoS One 2012, PMID:23028483. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants