Standard

Medication use (drugs affecting bone structure and mineralization)

BTNL2 · rs9268500

Where this position leads

Condition: Medication Use as a Genetic Trait

rs9268500 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs9268500 rs9268500 BTNL2

What the study found

Who was studied 7,870 European ancestry cases, 207,798 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.203 higher (95% confidence interval 0.13-0.27); p = 2 × 10−8.

How common The T allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — between genes, 1 kb from TSBP1-AS1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Medication use (drugs affecting bone structure and mineralization) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (drugs affecting bone structure and mineralization).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (drugs affecting bone structure and mineralization) compared to the general population.
Source

Questions about rs9268500

What is rs9268500?

rs9268500 is a single position in the genome, in or near the BTNL2 gene. Published research associates it with medication use (drugs affecting bone structure and mineralization). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9268500 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs9268500 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9268500 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (drugs affecting bone structure and mineralization) (rs9268500). MyGeneLog™. https://www.mygenelog.com/variants/rs9268500

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