Sensitive

Coronary heart disease

BTNL2 · rs9268402

Where this position leads

Condition: Coronary Artery Disease

rs9268402 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs9268402 rs9268402 BTNL2

What the study found

Who was studied 1,515 Han Chinese ancestry cases, 5,019 Han Chinese ancestry controls; replicated in 15,460 Han Chinese ancestry cases, 11,472 Han Chinese ancestry controls.

The effect Each copy of the G allele carried 1.16 times the odds of Coronary heart disease (95% confidence interval 1.12-1.20); p = 3 × 10−15.

How common The G allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of TSBP1-AS1.

What each result means

A/A No copy of the version the research linked to Coronary heart disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Coronary heart disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Coronary heart disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9268402

What is rs9268402?

rs9268402 is a single position in the genome, in or near the BTNL2 gene. Published research associates it with coronary heart disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9268402 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs9268402 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9268402 come from?

GWAS Catalog, Nat Genet 2012, PMID:22751097. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary heart disease (rs9268402). MyGeneLog™. https://www.mygenelog.com/variants/rs9268402

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