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Microscopic colitis

near PPIAP9 · rs9267445

What the study found

Who was studied 2,599 European ancestry cases, 552,343 European ancestry controls.

The effect Each copy of the C allele carried 1.80 times the odds of Microscopic colitis (95% confidence interval 1.7-2.0); p = 4 × 10−39.

How common The C allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 3.8 kb from PPIAP9.

What each result means

C/C Two copies of the version the research linked to Microscopic colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Microscopic colitis. That is a smaller link than two copies.
G/G No copy of the version the research linked to Microscopic colitis. This is the starting point the study compared everyone against.
Source

Questions about rs9267445

What is rs9267445?

rs9267445 is a single position in the genome, in or near the near PPIAP9 gene. Published research associates it with microscopic colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9267445 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9267445 come from?

GWAS Catalog, Journal of Crohn's & colitis 2024, PMID:37768647. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Microscopic colitis (rs9267445). MyGeneLog™. https://www.mygenelog.com/variants/rs9267445

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