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Who was studied 516 Turkish ancestry cases, 119 European ancestry cases, 462 Turkish ancestry controls, 993 European ancestry controls.
The effect
Each copy of the G allele carried 1.87 times the odds of Takayasu arteritis (95% confidence interval 1.50-2.34); p = 2 × 10−8.
How common The G allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of MICA-AS1.
What each result means
A/ANo copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs9266745 is a single position in the genome, in or near the HLA-B gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9266745 linked to?
On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.
Does rs9266745 affect how medicines work?
HLA-B carries pharmacogenomic findings for Abacavir, Allopurinol, Carbamazepine and oxcarbazepine. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs9266745 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9266745 come from?
GWAS Catalog, Arthritis & rheumatology (Hoboken, N.J.) 2015, PMID:25604533. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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