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Serum urate levels

near HLA-B · rs9266061

What the study found

Who was studied 219,768 East Asian ancestry individuals, 677,373 European ancestry individuals, 132,182 individuals.

The effect Each copy of the A allele shifted the measure 0.0223 higher (95% confidence interval 0.017-0.027); p = 1 × 10−18.

Where it sits Chromosome 6, band 6p21.33 — between genes, 2.4 kb from HLA-B.

What each result means

A/A Two copies of the version the research linked to Serum urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum urate levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum urate levels. This is the starting point the study compared everyone against.
Source

Questions about rs9266061

What is rs9266061?

rs9266061 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with serum urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9266061 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9266061 come from?

GWAS Catalog, Nature communications 2024, PMID:38658550. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Serum urate levels (rs9266061). MyGeneLog™. https://www.mygenelog.com/variants/rs9266061

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