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Phospholipids to total lipids ratio in large LDL

near HLA-B · rs9265942

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0455 lower (95% confidence interval 0.033-0.058); p = 4 × 10−12.

How common The C allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 6.6 kb from HLA-B.

What each result means

C/C Two copies of the version the research linked to Phospholipids to total lipids ratio in large LDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Phospholipids to total lipids ratio in large LDL. That is a smaller link than two copies.
G/G No copy of the version the research linked to Phospholipids to total lipids ratio in large LDL. This is the starting point the study compared everyone against.
Source

Questions about rs9265942

What is rs9265942?

rs9265942 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with phospholipids to total lipids ratio in large ldl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9265942 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9265942 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phospholipids to total lipids ratio in large LDL (rs9265942). MyGeneLog™. https://www.mygenelog.com/variants/rs9265942

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