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Free cholesterol to total lipids ratio in medium HDL

near HLA-B · rs9265620

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0279 higher (95% confidence interval 0.02-0.036); p = 7 × 10−13.

How common The T allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 22 kb from HLA-B.

What each result means

C/C No copy of the version the research linked to Free cholesterol to total lipids ratio in medium HDL. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Free cholesterol to total lipids ratio in medium HDL. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Free cholesterol to total lipids ratio in medium HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9265620

What is rs9265620?

rs9265620 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with free cholesterol to total lipids ratio in medium hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9265620 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9265620 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Free cholesterol to total lipids ratio in medium HDL (rs9265620). MyGeneLog™. https://www.mygenelog.com/variants/rs9265620

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