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Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia

CEP72 · rs924607

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia — no copies of the reported risk allele. (GWAS Catalog, JAMA 2015, PMID:25710658)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia. (GWAS Catalog, JAMA 2015, PMID:25710658)
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia compared to the general population. (GWAS Catalog, JAMA 2015, PMID:25710658)

Source: GWAS Catalog, JAMA 2015, PMID:25710658

Questions about rs924607

What is rs924607?

rs924607 is a single position in the genome, in or near the CEP72 gene. Published research associates it with vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs924607 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs924607 come from?

GWAS Catalog, JAMA 2015, PMID:25710658. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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