Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia
CEP72 · rs924607
2 4852217223123Reads by AI crawlersClaude5ChatGPT2Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others23Total48Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 53 European ancestry cases with peripheral neuropathy, 156 cases without peripheral neuropathy, 10 African ancestry cases with peripheral neuropathy, 33 African ancestry cases without peripheral neuropathy, 1 Asian ancestry case with peripheral neuropathy, 1 Asian ancestry case without peripheral neuropathy, 14 Hispanic cases with peripheral neuropathy, 30 Hispanic cases without peripheral neuropathy, 8 cases with peripheral neuropathy, 15 cases without peripheral neuropathy.
The effect
Each copy of the T allele carried 2.43 times the odds of Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia (95% confidence interval 1.70-3.49); p = 6 × 10−9.
Where it sits Chromosome 5, band 5p15.33 — in an intron of CEP72-DT.
What each result means
C/CNo copy of the version the research linked to Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs924607 is a single position in the genome, in or near the CEP72 gene. Published research associates it with vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs924607 linked to?
On MyGeneLog this position is linked to Acute Lymphoblastic Leukemia. The research behind each link, and its sources, are set out on that condition page.
Does having rs924607 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs924607 come from?
GWAS Catalog, JAMA 2015, PMID:25710658. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 4852217223123Reads by AI crawlersClaude5ChatGPT2Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others23Total48Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia (rs924607). MyGeneLog™. https://www.mygenelog.com/variants/rs924607