0 2321422327Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 4,086 European ancestry cases, 1,278,496 European ancestry controls, 1,055 East Asian ancestry cases, 177,671 East Asian ancestry controls, 2,696 African American or Afro-Caribbean cases, 136,842 African American or Afro-Caribbean controls.
The effect
Each copy of the A allele carried 0.90 times the odds of Keloid (95% confidence interval 0.873813773-0.936962518); p = 2 × 10−8.
Where it sits Chromosome 8, band 8q24.13 — in an intron of TRIB1AL.
What each result means
A/ATwo copies of the version the research linked to Keloid. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Keloid. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Keloid. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40835838 · open access
Questions about rs921721
What is rs921721?
rs921721 is a single position in the genome, in or near the near TRIB1 gene. Published research associates it with keloid. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs921721 linked to?
On MyGeneLog this position is linked to Keloid. The research behind each link, and its sources, are set out on that condition page.
Does having rs921721 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs921721 come from?
GWAS Catalog, Nature communications 2025, PMID:40835838. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2321422327Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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