Standard

Age-related hearing impairment

LMO7 · rs920701

Where this position leads

Condition: Age-Related Hearing Loss

rs920701 Condition: Age-Related Hearing Loss Age-Related Hearing Loss Condition rs920701 rs920701 LMO7

What the study found

Who was studied 147,997 European ancestry cases, 575,269 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0064 lower (95% confidence interval 0.0044-0.0084); p = 5 × 10−11.

How common The T allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 13, band 13q22.2 — in an intron of LMO7.

What each result means

C/C No copy of the version the research linked to Age-related hearing impairment. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Age-related hearing impairment. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Age-related hearing impairment. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs920701

What is rs920701?

rs920701 is a single position in the genome, in or near the LMO7 gene. Published research associates it with age-related hearing impairment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs920701 linked to?

On MyGeneLog this position is linked to Age-Related Hearing Loss. The research behind each link, and its sources, are set out on that condition page.

Does having rs920701 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs920701 come from?

GWAS Catalog, American journal of human genetics 2022, PMID:35580588. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age-related hearing impairment (rs920701). MyGeneLog™. https://www.mygenelog.com/variants/rs920701

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