Sensitive

2-Methylsuccinic acid levels in coronary artery disease

ACADS · rs9204

Where this position leads

Condition: Coronary Artery Disease

rs9204 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs9204 rs9204 ACADS

What the study found

Who was studied 1,551 Han Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.37 higher (95% confidence interval 0.29-0.45); p = 3 × 10−20.

How common The A allele had a frequency of about 88% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in the 3′ untranslated region of ACADS.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of 2-Methylsuccinic acid levels in coronary artery disease compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with 2-Methylsuccinic acid levels in coronary artery disease.
G/G Published research associates this genotype with typical/baseline likelihood of 2-Methylsuccinic acid levels in coronary artery disease — no copies of the reported risk allele.
Source

Questions about rs9204

What is rs9204?

rs9204 is a single position in the genome, in or near the ACADS gene. Published research associates it with 2-methylsuccinic acid levels in coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9204 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs9204 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9204 come from?

GWAS Catalog, Clinical and translational medicine 2021, PMID:33634981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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2-Methylsuccinic acid levels in coronary artery disease (rs9204). MyGeneLog™. https://www.mygenelog.com/variants/rs9204

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