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Monocyte percentage of white cells

FAM46A · rs915125

Where this position leads

Condition: Blood Cell Counts

rs915125 Condition: Blood Cell Counts Blood Cell Counts Condition rs915125 rs915125 FAM46A

What the study found

Who was studied 170,494 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0406 higher (95% confidence interval 0.033-0.048); p = 2 × 10−24.

How common The T allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 6, band 6q14.1 — between genes, 0.9 kb from TENT5A.

What each result means

C/C No copy of the version the research linked to Monocyte percentage of white cells. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Monocyte percentage of white cells. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Monocyte percentage of white cells. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs915125

What is rs915125?

rs915125 is a single position in the genome, in or near the FAM46A gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs915125 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs915125 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs915125 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte percentage of white cells (rs915125). MyGeneLog™. https://www.mygenelog.com/variants/rs915125

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