Sensitive

Breast cancer

ESR1 · rs910416

Where this position leads

Condition: Breast Cancer

rs910416 Condition: Breast Cancer Breast Cancer Condition rs910416 rs910416 ESR1

What the study found

Who was studied 17,881 European ancestry female cases, 219,656 European ancestry female controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 6 × 10−16.

Where it sits Chromosome 6, band 6q25.2 — inside ESR1.

What each result means

C/C Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs910416

What is rs910416?

rs910416 is a single position in the genome, in or near the ESR1 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs910416 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs910416 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs910416 come from?

GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs910416). MyGeneLog™. https://www.mygenelog.com/variants/rs910416

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