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Childhood asthma with severe exacerbations

IKZF3 · rs907091

Where this position leads

Condition: Asthma

rs907091 Condition: Asthma Asthma Condition rs907091 rs907091 IKZF3

What the study found

Who was studied 2,866 European ancestry cases, 65,415 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.484 higher (95% confidence interval 0.43-0.54); p = 2 × 10−63.

Where it sits Chromosome 17, band 17q12 — in the 3′ untranslated region of IKZF3.

What each result means

C/C No copy of the version the research linked to Childhood asthma with severe exacerbations. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Childhood asthma with severe exacerbations. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Childhood asthma with severe exacerbations. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs907091

What is rs907091?

rs907091 is a single position in the genome, in or near the IKZF3 gene. Published research associates it with childhood asthma with severe exacerbations. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs907091 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs907091 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs907091 come from?

GWAS Catalog, Nature communications 2020, PMID:33328473. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Childhood asthma with severe exacerbations (rs907091). MyGeneLog™. https://www.mygenelog.com/variants/rs907091

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