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Triglycerides in medium HDL

NEIL2 · rs904009

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs904009 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs904009 rs904009 NEIL2

What the study found

Who was studied 434,646 British ancestry individuals, 8,796 British Central/South Asian individuals, 6,573 British African individuals.

The effect Each copy of the C allele shifted the measure 0.03 mmol/L lower (95% confidence interval 0.03-0.03); p = 2 × 10−44.

Where it sits Chromosome 8, band 8p23.1 — in an intron of NEIL2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Triglycerides in medium HDL — no copies of the reported risk allele.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides in medium HDL.
C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides in medium HDL compared to the general population.
Source

Questions about rs904009

What is rs904009?

rs904009 is a single position in the genome, in or near the NEIL2 gene. Published research associates it with triglycerides in medium hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs904009 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs904009 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs904009 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides in medium HDL (rs904009). MyGeneLog™. https://www.mygenelog.com/variants/rs904009

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