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Heel bone mineral density

HRH1 · rs901865

Where this position leads

Condition: Heel Bone Mineral Density

rs901865 Condition: Heel Bone Mineral Density Heel Bone Mineral Density Condition rs901865 rs901865 HRH1

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Heel bone mineral density — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Heel bone mineral density.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Heel bone mineral density compared to the general population.
Source
An atlas of genetic influences on osteoporosis in humans and mice
Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J
and 47 more — show all
Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG, Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB
23andMe Research Team
Nature genetics · 2019 · PMID 30598549 · open access

Questions about rs901865

What is rs901865?

rs901865 is a single position in the genome, in or near the HRH1 gene. Published research associates it with heel bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs901865 linked to?

On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.

Does having rs901865 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs901865 come from?

GWAS Catalog, Nat Genet 2018, PMID:30598549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants